Table 1. Global reductions in deaths in children younger than 5 years associated with vaccines, 1990–2019.

Vaccine	Reduction in deaths associated with vaccines (95% CI)a
	No. of deaths in millions	% of deaths	Mortality rate per 1 000 live births
DTP3 vaccine	46.7 (30.0 to 72.7)	13.0 (10.4 to 15.9)	11.4 (7.3 to 17.7)
Measles vaccine	37.9 (25.4 to 56.8)	10.6 (8.8 to 12.4)	9.3 (6.2 to 13.9)
Hib3 vaccine	1.6 (1.2 to 2.0)	0.4 (0.4 to 0.4)	0.4 (0.3 to 0.5)
Rotavirus vaccine	0.7 (0.6 to 0.9)	0.2 (0.2 to 0.2)	0.2 (0.2 to 0.2)
Total	86.9 (57.2 to 132.4)	24.2 (19.8 to 28.9)	21.2 (14.0 to 32.3)

CI: confidence interval; DTP3: diphtheria–tetanus–pertussis vaccine three doses; Hib3: Haemophilus influenzae type b vaccine three doses.

^a Compared to a scenario with no vaccines.

Notes: Percentage reduction in deaths associated with vaccines = (reduction in the number of deaths associated with vaccines/estimated number of deaths without vaccines) × 100. Reduction in under-5 mortality rate per 1000 live births = (reduction in the number of deaths associated with vaccines/number of live births) × 1000.