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. 2005 Apr 28;5:12. doi: 10.1186/1475-2867-5-12

Table 2.

Omega-3 Fatty Acid Enriched Diet (n-3) and Gamma Irradiation Therapy (IR) on Blood Counts, (means ± SEM)

Therapy Group n WBC × 103/μL RBC × 106/μL Platelets × 103/μL Micronuclei (%RBC)
Early Kill1
n-6 4 2.91 ± 0.83 9.08 ± 0.07 584 ± 76 1.3 ± 0.04
n-6/IR 4 0.11 ± 0.01 7.50 ± 0.16 389 ± 17 1.2 ± 0.03
n-3 7 2.02 ± 0.30 8.45 ± 0.12 634 ± 51 1.2 ± 0.03
n-3/IR 4 0.16 ± 0.03 7.66 ± 0.07 358 ± 78 1.5 ± 0.04
Late Kill2
n-6 8 1.85 ± 0.37 8.30 ± 0.14 551 ± 83 1.6 ± 0.06
n-6/IR 13 1.48 ± 0.32 7.06 ± 0.16 973 ± 98 1.1 ± 0.01
n-3 16 2.85 ± 0.42 8.31 ± 0.20 582 ± 61 1.3 ± 0.04
n-3/IR 10 0.92 ± 0.18 6.10 ± 0.40 918 ± 131 0.9 ± 0.03

1Mice euthanized one day after last irradiation treatment.

2Mice euthanized 22 days after last irradiation treatment.

Results of Statistical Analyses:

1. At one day after the end of irradiation therapy, there were significant decreases in WBC, RBC, and platelet counts due to the irradiation. There were no other significant differences at p < 0.01.

2. At 22 days after the end of irradiation therapy, WBC and RBC counts were still significantly decreased and there was a significant increase in platelet counts due to irradiation. There were no other significant differences at p < 0.01.