Table 3.

Mendelian randomization estimates for the association between gut microbiota and endometrial cancer.

Bacterial taxa (exposure)	Outcome	MR method	No. SNP	P-value	OR	95%CI
Family Acidaminococcaceae	EC	IVW	7	.032	1.228	1.02–1.48
Genus Turicibacter	EC	IVW	10	.014	0.843	0.73–0.97
Family Acidaminococcaceae	ECEH	IVW	7	.037	1.270	1.01–1.59
Family Lactobacillaceae	ECEH	IVW	9	.019	0.838	0.72–0.97
Genus Coprococcus3	ECEH	IVW	9	.028	0.772	0.61–0.97
Genus Dorea	ECEH	IVW	10	.016	0.762	0.61–0.95
Genus Flavonifractor	ECEH	IVW	5	.008	0.716	0.56–0.92
Genus Lactobacillus	ECEH	IVW	10	.004	0.813	0.71–0.94
Genus Paraprevotella	ECEH	IVW	13	.028	0.870	0.77–0.98
Genus Ruminiclostridium9	ECEH	IVW	9	.037	0.759	0.59–0.98
Genus Turicibacter	ECEH	IVW	10	.022	0.829	0.71–0.97
Genus Peptococcus	ECNEH	IVW	12	.017	1.419	1.07–1.89

CI = confidence interval, EC = endometrial cancer, ECEH = endometrial cancer endometrioid histology, ECNEH = endometrial cancer non-endometrioid histology, IVW = inverse variance weighted, MR = Mendelian randomization, OR = odds ratio, SNPs = single nucleotide polymorphisms.