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. 2024 Mar 28;19(3):e0292189. doi: 10.1371/journal.pone.0292189

Fig 4. The effect of p53 dosage on Kras-driven lung tumorigenesis.

Fig 4

Percentage of Rosa26CreERT2/+ mice with the indicated grades of peripheral atypical alveolar hyperplasia (AAH) detected in each genotype (n = 5–8). Statistical comparisons of the severity of peripheral AAH in each genotype with versus without Super p53 allele were done using Chi-square test. ****: p-value <0.0001. The incidence, grading, and number of lesions in the lung are provided in S5 Appendix.