Table 1. Demographic and clinical characteristics of 10 patients with Acanthamoeba infection who performed nasal rinsing, United States, 1994–2022.
| Demographic | Value |
|---|---|
| Median age (range), y |
60 (32–80) |
| Sex | |
| M | 7 |
| F |
3 |
| Race | |
| White | 5 |
| Black | 2 |
| Asian/Pacific Islander | 1 |
| Unknown |
2 |
| Ethnicity | |
| Hispanic | 1 |
| Non-Hispanic | 4 |
| Unknown |
5 |
| Disease manifestation, confirmed or suspected† | |
| Rhinosinusitis | 9 |
| GAE | 6 |
| Cutaneous | 6 |
| Osteomyelitis | 3 |
| Pulmonary | 1 |
| Endophthalmitis |
1 |
| Diagnostic method† | |
| PCR | 7 |
| Histopathology | 6 |
| Immunohistochemical staining | 5 |
| Indirect immunofluorescence |
2 |
| Specimens tested† | |
| Skin | 6 |
| Brain | 4 |
| Sinus | 4 |
| Bone |
3 |
| Genotype | |
| T4 | 4 |
| T1 | 1 |
| Unknown |
5 |
| Underlying conditions† | |
| Chronic sinusitis | 7 |
| Cancer‡ | 5 |
| Chronic kidney disease | 5 |
| HIV/AIDS | 2 |
| Solid organ transplant | 2 |
| Stem cell transplant | 1 |
| Microscopic Polyangiitis |
1 |
| Outcome | |
| Survived | 7 |
| Died | 3 |
*Values are no. (%) patients except as indicated. GAE, granulomatous amebic encephalitis. †Some patients may have had multiple disease manifestations, multiple diagnostic methods, or multiple comorbid conditions. ‡Four chronic lymphocytic leukemia, 1 acute myeloid leukemia.