Table 2. Structures and potencies of selected hits.

All compounds are numbered and are prefixed with an “I” for inhibitors and “A” for activators. IC₅₀ and EC₅₀ values are the triplicate means ± SEM derived from fitting a four-parameter sigmoidal dose-response curve of a 7-point dose-response titration (1:2, 300 μM - 0.4 μM) against PLD4.

Compound	I3	A2	A3	A4
Potency (μM)	39.6 ±4.6	35.7 ±4.2	20.2 ±3.3	38.6 ± 9.9