Table 1.
Baseline demographics, clinical characteristics, and cTn-I levels in the study subjects.
| Variables | Angiographic CAD classification |
P-value⁎ | ||||
|---|---|---|---|---|---|---|
| None (n = 61) | Mild (n = 35) | Moderate (n = 53) | Severe (n = 215) | Total (n = 364) |
||
| Demographics | ||||||
| Age, mean (SD, years) | 53 (12) | 57 (15) | 68 (11) | 63 (12) | 62 (13) | <0.001 |
| Female, n (%) | 28 (46) | 14 (40) | 23 (43) | 84 (39) | 149 (41) | 0.78 |
| African American, n (%) | 56 (92) | 34 (97) | 48 (91) | 177 (82) | 315 (86) | 0.005 |
| CAD Risk factors | ||||||
| Smoking, n (%) | 34 (56) | 14 (40) | 20 (38) | 116 (54) | 184 (51) | 0.08 |
| Diabetes mellitus, n (%) | 21 (34) | 14 (40) | 33 (62) | 164 (76) | 232 (64) | <0.0001 |
| Hypertension, n (%) | 55 (90) | 31 (89) | 48 (91) | 199 (93) | 333 (91) | 0.40 |
| Peripheral arterial disease, n (%) | 9 (15) | 4 (11) | 8 (15) | 72 (33) | 93 (26) | 0.0005 |
| Hyperlipidemia, n (%) | 13 (21) | 4 (11) | 21 (40) | 111 (52) | 149 (41) | <0.0001 |
| Baseline cTn-I | ||||||
| LoD 0.02 ng/mL, n (%) | 27 (44) | 7 (20) | 8 (15) | 15 (7) | 57 (16) | <0.0001 |
| Indeterminate 0.02–0.19 ng/mL, n (%) | 33 (54) | 26 (74) | 42 (79) | 131 (61) | 232 (64) | 0.078 |
| 99th percentile URL ≥ 0.20 ng/mL, n (%) | 1 (2) | 2 (6) | 3 (6) | 69 (32) | 75 (20) | 0.0001 |
CAD, coronary artery disease; cTn-I, cardiac troponin I; LoD, limit of detection; n, number; SD, standard deviation; URL, upper reference limit.
⁎
P-value <0.05 was considered statistically significant.