Table 2.

Univariate linear regression analysis of the number of nuclei visualized with optical coherence microscopy at E3.0 in relation to the number of cells in the mouse embryos and the size of their outgrowths.

Output parameters	No. of embryos			Coefficient	95% CI		P-value
All embryos at E4.0
Total no. of cells	97			2.87	2.33	3.41	<0.001
Only blastocysts at E4.0
Total no. of cells	70			2.38	1.69	3.07	<0.001
No. of TE cells	70			2.04	1.45	2.63	<0.001
No. of ICM cells	70			0.33	0.12	0.54	0.002
No. of EPI cells	70			0.20	0.01	0.39	0.039
No. of PE cells	70			0.13	0.06	0.21	0.001
All embryos at E5.0
Total no. of cells	117			3.25	2.41	4.08	<0.001
Only blastocysts at E5.0
Total no. of cells	103			2.43	1.58	3.29	<0.001
No. of TE cells	103			2.06	1.36	2.75	<0.001
No. of ICM cells	103			0.38	0.13	0.62	0.003
No. of EPI cells	103			0.15	0.02	0.28	0.025
No. of PE cells	103			0.23	0.09	0.36	0.001
Outgrowths
Outgrowth area ($\mathrm{\mu }$m2)		84	5693.1		3489.1	7897.1		<0.001

E3.0, E4.0, E5.0—72, 96, and 120 h after onset of insemination.

EPI: epiblast; ICM: inner cell mass; PE: primitive endoderm; TE: trophectoderm.