Figure 2.

LV MM and RV MM Hydrogels Mitigate Negative RV Remodeling and Improve RV Function

(A) Short axis: representative images of study animals show the right ventricle (upper left of each image) of each treatment group at end-diastole. RV volumes, ejection fraction, and morphology were quantified by assessing changes in RV end-diastolic volume (RVEDV) (B), RV end-systolic volume (RVESV) (C), RV ejection fraction (RVEF) (D), LV end-diastolic eccentricity index (LVEDEI) (E), LV end-systolic eccentricity index (LVESEI) (F), and RV free wall thickness (G). Scale bar = 2 mm. Data are presented as mean ± SEM. N = 8-9. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001 compared with saline-treated animals with 1-way analysis of variance with Tukey’s post hoc test. Abbreviations as in Figure 1.