Figure 3.

Functional Improvements Correlate Between Imaging Modalities

Data from echocardiography and magnetic resonance imaging were compared to show the conserved functional benefit of each hydrogel. (A and B) Animals treated with LV MM or RV MM hydrogels showed clear separation from saline control group by exhibiting increased TAPSEs and reduced RVEDV (r = –0.71; P ≤ 0.001) (A) and RVESV (r = –0.87, P ≤ 0.001) (B). (C) Animals treated with the LV MM or RV MM hydrogel also showed clustering improvements in the 2 main measures of RV function (RVEF and TAPSE) (r = 0.85; P ≤ 0.001) being clearly separated from the saline-treated group. (D) Correlation plot reveals that animal treated with LV MM or RV MM hydrogels clustered with thinner right ventricles and higher TAPSEs than saline-treated animals (r = –0.91; P ≤ 0.001). N = 8 to 9. Abbreviations as in Figures 1 and 2.