Table 2.

Univariate and multivariate Cox regression analyses of potential prognostic variables in GC patients.

Variables	Subset	Hazard ratio for OS (95%CI)	p value
Univariate analysis (n = 80)
Age (years)	<60 vs ≥60	–	0.685
Gender	Male vs Female	–	0.932
Invasion depth	T1 + T2 vs T3 + T4	–	0.221
Tumor differentiation	Poor vs Moderate/Well	–	0.092
Lymphatic metastasis	N0 + N1 vs N2 + N3	1.512 (1.023–2.235)	0.038*
Distal metastasis	Absent vs Present	5.446 (1.589–18.666)	0.007*
TNM stage	I + II vs III + IV	2.825 (1.322–6.037)	0.007*
Tumor size (cm)	<5 vs ≥5	3.297 (1.295–8.395)	0.012*
circUSP1 level	Low vs High	3.213 (1.260–8.192)	0.015*
Multivariate analysis (n = 80)
Lymphatic metastasis	N0 + N1 vs N2 + N3	–	0.490
Distal metastasis	Absent vs present	–	0.113
TNM stage	I + II vs III + IV	–	0.501
Tumor size (cm)	< 5 vs ≥ 5	2.974 (1.130–7.826)	0.027*
circUSP1 level	Low vs High	2.777 (1.051–7.336)	0.039*

Bold values indicate significance at p < 0.05.