Table 3.

Association of patient- and tumor characteristics with survival (multivariate analysis)

	HR (95% CI)	P value
Progression-free survival
Multifocality	1.74 (1.00–3.02)	0.049
Extent of resection
Gross-total vs. biopsy	0.23 (0.13–0.42)	< 0.001
Subtotal vs. biopsy	0.51 (0.29–0.90)	0.021
Strong EGFR expression	6.15 (2.15–17.60)	0.001
Overall survival
Extent of resection
Gross-total vs. biopsy	0.16 (0.08–0.31)	< 0.001
Subtotal vs. biopsy	0.37 (0.19–0.71)	0.03
WHO Grade, II vs. III	0.35 (0.18–0.70)	0.003
Strong EGFR expression	7.33 (2.21–24.35)	0.001
Perioperative complication	2.00 (1.05–3.79)	0.034
TERT mutated vs. wild-type	13.58 (1.69–109.04)	0.014

Multivariate Cox Proportional Hazards Regression analysis, backward conditional selection method used, step 6 is displayed for PFS and step 4 for OS.