Table 2.
Univariable and multivariable Cox analysis of atypical meningioma patients.
| Univariable analysis | Multivariable analysis* | |||
|---|---|---|---|---|
| HR (95% CI) | p | HR (95% CI) | p | |
| Age, years | 1.06 (1.05, 1.07) | <0.001 | 1.06 (1.05, 1.07) | <0.001 |
| Gender | ||||
| Female | Ref | Ref | ||
| Male | 1.26 (1.02, 1.56) | 0.029 | 1.32 (1.05, 1.65) | 0.016 |
| Race | ||||
| White | Ref | Ref | ||
| Black | 1.47 (1.12, 1.93) | 0.005 | 1.47 (1.11, 1.95) | 0.005 |
| Others | 0.69 (0.47, 1.01) | 0.057 | 0.72 (0.49, 1.05) | 0.091 |
| Year of diagnosis | ||||
| 2004–2008 | Ref | |||
| 2009–2016 | 0.97 (0.76, 1.24) | 0.792 | ||
| 2017–2019 | 1.21 (0.82, 1.80) | 0.337 | ||
| Tumor size, mm | 1.01 (1.01, 1.02) | <0.001 | 1.01 (1.01, 1.02) | <0.001 |
| Primary site | ||||
| Cerebral meninges | Ref | |||
| Brian | 0.73 (0.18, 2.92) | 0.653 | ||
| Laterality | ||||
| Left | Ref | |||
| Right | 1.17 (0.94, 1.45) | 0.149 | ||
| Paired site | 1.03 (0.60, 1.74) | 0.923 | ||
| Marital status | ||||
| Married | Ref | Ref | ||
| Divorced | 1.02 (0.67, 1.55) | 0.936 | 1.04 (0.68, 1.59) | 0.866 |
| Widowed | 3.76 (2.85, 4.97) | <0.001 | 2.08 (1.52, 2.84) | <0.001 |
| Single | 1.33 (1.00, 1.76) | 0.051 | 1.78 (1.33, 2.39) | <0.001 |
| Other | 1.83 (1.19, 2.80) | 0.006 | 1.87 (1.21, 2.88) | 0.005 |
| Surgery type | ||||
| GTR | Ref | Ref | ||
| STR | 1.41 (1.15, 1.75) | 0.001 | 1.43 (1.16, 1.77) | <0.001 |
| ABRT | ||||
| No | Ref | Ref | ||
| Yes | 1.02 (0.81, 1.29) | 0.855 | 1.21 (0.96, 1.54) | 0.115 |
*ABRT and variables with p < 0.1 in univariable analysis were enrolled in the multivariable analysis. GTR, gross total resection; STR, subtotal resection; ABRT, adjuvant beam radiation therapy; HR, hazard ratio; 95% CI, 95% confidence interval.