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. 2024 Mar 15;15:1365206. doi: 10.3389/fimmu.2024.1365206

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Copyright © 2024 Li, Yan, Zhang, Pan and Guo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of single-nuclei RNA-Seq data. (A) A uniform manifold approximation and projection map showing the 19 cell types found using unsupervised analysis. The data is sourced from post-mortem lung tissue samples of COVID-19 fatal cases and seven healthy donors. (B) The 19 cell type proportions. (C) Dot plot illustrating the hub ARDS-ARDEGs expression levels in several cell types. (D) A violin plot showing how COVID-19 patients and healthy donors differ in the expression of TYMS in endothelial cells.