Table 2.

Common drug targets and similarities.

Target	SLE	RA	pSS	SSc	LVV	AAV	IIM
Type I IFN/IFNR	✓		✓	✓
IL-17/IL-17R				✓	✓
GM-CSFR		✓			✓
BAFF/BAFF receptor	✓		✓	✓
CD40/40L	✓	✓	✓
JAK/STAT	✓	✓	✓	✓	✓	✓	✓
IL-6/IL-6R		✓		✓
CD20	✓	✓	✓	✓	✓	✓	✓
CD19	✓			✓			✓
CD38	✓					✓

AAV, ANCA-associated vasculitis; GM-CSFR, GM-CSF receptor; IFNR, interferon receptor; IL-6R, IL-6 receptor; IL17R, IL-17 receptor; IIM, idiopathic inflammatory myopathy; LVV, large-vessel vasculitis; pSS, primary Sjögren’s syndrome; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; SSc, systemic sclerosis.