FIG. 1.

Growth of cells in the presence of 1d-3-deoxy-3-fluoro-myo-inositol. Normal F111 (•) and polyomavirus-transformed PyF (▪) cells were plated at subconfluency in myo-inositol-free DMEM containing 10% dialyzed calf serum, 5 μM myo-inositol, and 1d-3-deoxy-3-fluoro-myo-inositol at the concentrations shown and grown for 4 days. Growth was measured by the MTT viability assay as described in Methods and Materials and plotted as a percentage of that of the control without 1d-3-deoxy-3-fluoro-myo-inositol.