Table 3.
Univariate and multivariate cox analysis of overall survival of the training cohort.
| Variables | Univariate analysis |
Multivariate analysis |
||||
|---|---|---|---|---|---|---|
| HR | 95%Cl | p-value | HR | 95%Cl | p-value | |
| Age | 1.02 | 1.012–1.028 | <0.001 | 1.009 | 1.000–1.017 | 0.029 |
| Race | ||||||
| White | 1.000 | |||||
| Black | 1.178 | 0.937–1.481 | 0.162 | |||
| Asian&Pacific Islander | 1.319 | 0.754–2.309 | 0.332 | |||
| American Indian&Alaska Nativ | 1.689 | 0.236–12.065 | 0.602 | |||
| T stage | ||||||
| I ∼ III | 1.000 | |||||
| IV | 1.354 | 1.104–1.660 | 0.004 | 1.348 | 1.090–1.667 | 0.006 |
| Nodal status | ||||||
| N0 | 1.000 | |||||
| N+ | 0.771 | 0.600–0.992 | 0.043 | |||
| Marital status | ||||||
| Single | 1.000 | 1.000 | ||||
| Married | 0.700 | 0.57–0.860 | <0.001 | 0.856 | 0.690–1.061 | 0.155 |
| Laterality | ||||||
| Left | 1.000 | |||||
| Right | 1.152 | 0.943–1.408 | 0.165 | |||
| Bilateral | 0.954 | 0.134–6.817 | 0.963. | |||
| Histologic type | ||||||
| IDC | 1.000 | |||||
| ILC | 1.729 | 0.714–4.185 | 0.225 | |||
| Other | 0.830 | 0.539–1.278 | 0.396 | |||
| Extrahepatic metastasis sites | ||||||
| 0 | 1.000 | 1.000 | ||||
| 1 | 1.383 | 1.092–1.752 | 0.007 | 1.396 | 1.096–1.778 | 0.007 |
| 2 | 2.293 | 1.720–3.058 | <0.001 | 2.095 | 1.556–2.821 | <0.001 |
| 3 | 3.350 | 2.076–5.406 | <0.001 | 3.729 | 2.234–6.223 | <0.001 |
| Surgery | ||||||
| No | 1.000 | 1.000 | ||||
| Yes | 0.615 | 0.498–0.760 | <0.001 | 0.733 | 0.586–0.916 | 0.006 |
| Radiation | ||||||
| N/unknown | 1.000 | |||||
| Yes | 0.873 | 0.692–1.101 | 0.251 | |||
| Chemotherapy | ||||||
| NO/unknown | 1.000 | 1.000 | ||||
| Yes | 0.200 | 0.156–0.257 | <0.001 | 0.248 | 0.188–0.327 | <0.001 |
IDC: invasive ductal carcinoma; ILC: invasive lobular carcinoma; IQR: interquartile range; CI: confidence interval; HR: hazard ratios.