Table 2. Treatment and Outcomes of Individuals With and Without Immunosuppression With Neuroinvasive West Nile Virus Infection.
Adjunctive therapy | Patients, No. (%) | ||
---|---|---|---|
Not immunosuppressed (n = 72) | Immunosuppressed (n = 43) | Total (N = 115) | |
None | 52 (72) | 15 (35) | 67 (58) |
Any single agent (IVIg, interferon-alfa, ribavirin) | 16 (22) | 13 (30) | 29 (25) |
Any combination of agents | 4 (6) | 15 (35) | 19 (16) |
Interferon-alfa | 5 (7) | 16 (37) | 21 (18) |
IVIg | 12 (17) | 24 (56) | 36 (31) |
Other managements | |||
ICU admission | 24 (33) | 26 (61) | 50 (44) |
Mechanical ventilation | 22 (31) | 24 (56) | 46 (41) |
Outcome | |||
Hospital length of stay, median (IQR), d [No. missing] | 8 (5-20) [1] | 16 (11-26) [0] | 12 (6-23) [1] |
90-Day mortality, | 5 (7) | 12 (28) | 17 (15) |
Abbreviations: ICU, intensive care unit; IVIg, intravenous immunoglobulin.