Table 2.

Effect of amount of ¹⁷⁷Lu-PSMA-617 on TIA.

Amount		7.1×107 [Bq]	7.1×108 [Bq]	7.1×109 [Bq]
Time integrated activity (TIA) [MBq.min]	Released drug in tumor	13 × 103	13 × 104	13 × 105
	Implant	0.68 × 103	0.68 × 104	0.68 × 105
Absorbed dose [Gy]	Released drug in tumor	4.56	45.6	456
	Implant	0.23	2.3	23
Survival probability (%)	Released drug in tumor	19%	1.15 × 10-45%	0%
	Implant	96%	53%	3× 10-14%
Time integrated activity [MBq.min]	Drug in normal tissue	52 × 10-4	52 × 10-3	52 × 10-2