Figure 12. Examples of persistent avascular retina (PAR) and long-term sequelae of ROP.

(A) Combined tractional and exudative detachment in an 18 year-old with a history of untreated ROP whose fellow eye was phthisical from ROP. (B) Ultra-widefield fluorescein angiogram (UWFFA) demonstrating PAR (asterisks) in a 7 year-old child with a history of spontaneously regressed ROP. Note the abnormal vascular configuration, particularly inferotemporally (circle). (C) UWFFA from a 7 year-old with spontaneously regressed ROP but with PAR and leakage in incompletely regressed stage 3 inferotemporally (asterisks). (D) Ultra-widefield fundus image (left side) displays an incompletely regressed ridge (white arrowheads) with PAR (asterisks) in a 15 year-old child with a history of extreme prematurity and no prior ROP treatment. Two years later (right side), the patient presented with a macula-involving rhegmatogenous detachment. The fellow eye had a similar appearance and disease course. (E) Optical coherence tomography angiography (OCTA) image of an incompletely developed foveal contour (left) and poorly-defined foveal avascular zone (right) in a 7 year-old with history of type 1 ROP treated with laser.