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. Author manuscript; available in PMC: 2024 Mar 29.
Published in final edited form as: Ophthalmology. 2021 Jul 8;128(10):e51–e68. doi: 10.1016/j.ophtha.2021.05.031

Figure 7. Aggressive retinopathy of prematurity (A-ROP).

Figure 7.

(A) A-ROP with severe vasoconstriction, capillary nonperfusion, non-physiologic dilated vascular loops and arterio-venous shunts, and plus disease in zone I. (B) A-ROP with border between vascular and avascular retina in zone I, dilated vascular loops (white arrows), diffuse flat extraretinal neovascularization most prominent superotemporally, and severe plus disease. Note absence of a typical stage 3 lesion. (C) A-ROP in zone I with severe plus disease, flat extraretinal neovascularization with fibrosis and early contraction superiorly (white arrowheads), and intraretinal and vitreous hemorrhage superotemporally. (D) and (E) are two examples of wide-angle fundus photographs (left sides) demonstrating A-ROP with ill-defined junction between vascular and avascular retina in zone I (white arrows), and severe plus disease. Fluorescein angiography (right sides) demonstrate significant vaso-obliteration with capillary nonperfusion. Note that there are no typical ROP lesion appearances and that there are vaso-attenuated areas posterior to the ridge.