Figure 3.

Crystallographic fragment screening comprehensively explores the binding surface of proteins. Overlay of fragment hits from four recent screening campaigns conducted at the DLS XChem facility by SGC Oxford. The structures are available from the PDB under the provided group deposition ID. Additional information about the targets and fragment hits can be found at the SGC website (https://www.thesgc.org/tep). Results from all SGC Oxford fragment campaigns can be accessed via Fragalysis (https://fragalysis.diamond.ac.uk).