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. 2024 Mar 14;15:1366368. doi: 10.3389/fendo.2024.1366368

Table 2.

Barriers to initiating insulin therapy.

Conditioning factor Barrier Strategy
Patient - Adherence
- Perception of failure
- Use of long-acting insulin
- Dose recall systems

- Diabetes education program
Social environment - Social rejection - Community education
Treatment - Dosage



- Hypoglycemia









- Method of administration




- Weight Gain
- Use of simple adjustment guidelines
- Implementation of FGM/CGM systems
- Documentation of episodes by the patient
- Determination of a greater number of self-monitoring blood glucose.
- Implementation of FGM/CGM systems
- Education on signs and symptoms
- Adjustments in physical exercise
- Instruction in the guidelines for dealing with hypoglycemia.
- Simple, intuitive devices adapted to different physical limitations.
- Instruction in management technique.
- Design of specific devices for patients with needle phobia.
- Healthy eating education.
- Prescription of physical exercise
- Choice of type of insulin based on the reported weight evolution.
Professional - Healthcare team experience




- Clinical Guidelines of Scientific Societies
- Instruction and education of entire healthcare team.
- Constant review of glycemic control goals
- Proper device handling and management technique
- Efficacy of insulin as an initial control tool in severe hyperglycemia.
- Efficacy in certain diabetes profiles, such as diabetes secondary to the use of corticosteroids.

CGM, Continuous Glucose Monitoring; FGM, Flash Glucose Monitoring.