Table 2.
Basic features of included studies.
| Included studies | Number | M/F | Average age | Course of disease | Outcomes | |||
|---|---|---|---|---|---|---|---|---|
| (T/C) | T | C | T | C | T | C | ||
| Megna et al. (37) | 15/15 | 8:7 | 7:8 | 58.9 ± 5.4 | 59.3 ± 6.2 | - | - | (1) (4) (8) (9) (10) |
| Santamato et al. (38) | 16/16 | 7:9 | 6:10 | 64.4 ± 6.09 | 63.1 ± 7.03 | 10.5 ± 2.12(m) | 9.3 ± 3.97(m) | (1) (4) (7) |
| Lu (41) | 39/39 | 26:13 | 26:13 | 59.04 ± 4.43 | 58.95 ± 4.38 | 14.82±2.72(d) | 14.74±2.67(d) | (1) (2) (4) (6) |
| Liang et al. (40) | 30/30 | 17:13 | 16:14 | 49.93 ± 11.23 | 50.09 ± 11.07 | 60.07±11.13 (d) | 50.09±11.07(d) | (1) (2) (3) |
| Duan et al. (39) | 18/18 | 8:10 | 9:9 | 51.8 ± 6.2 | 52.6 ± 7.9 | 90.5±19.4(d) | 87.5±18.7(d) | (1) (2) (3) (5) |
| Wang et al. (42) | 20/20 | 9:11 | 11:9a | 52.18 ± 13.66 | 51.23±14.24a | 7.61±3.50(m) | 7.98±3.05(m)a | (1) (2) (3) |
| 12:8b | 50.89±15.16b | 8.02±3.17(m)b | ||||||
T is the treatment group; C is the control group; “-” indicates no report; (1) MAS score; (2) FMA score; (3) MBI score; (4) VAS score; (5) PROM; (6) BBS rating; (7) SFS score; (8) muscle tone; (9) Muscle stiffness; (10) Adverse reactions. Wang et al. included two control groups, aindicates the conventional rehabilitation group, bindicates conventional rehabilitation combined with BTX-A; d = day; m = mouth.