. Author manuscript; available in PMC: 2025 Jan 1.

Published in final edited form as: Eur J Neurosci. 2023 Dec 6;59(1):82–100. doi: 10.1111/ejn.16200

TABLE 2.

Hierarchical multiple linear regression results for CRF and cortical thickness by age group.

	Cortical thickness
	ROI	ß	95%CI	t(52)	p_FDR	ΔR²	F(4,51)	Model R²
YA n = 56	Left ERC	.25 ^**	.10–.41	3.30	.01 ^**	.17	2.39	.20
	Left PHC	.18 ^*	.03–.33	2.36	.04 ^*	.09	2.18	.15
	Left PRC	.23 ^*	.02–.44	2.64	.03 ^*	.11	2.50	.16
	Right ERC	.07	−.13–.28	.70	.56	.01	.47	.04
	Right PHC	.10	−.06–.26	1.29	.30	.03	.89	.07
	Right PRC	.06	−.14–.25	.58	.56	<.01	.36	.03
	ROI	ß	95%CI	t(39)	p_FDR	ΔR²	F(5,40)	Model R²
OA n = 44	Left ERC	−.02	−.27–.21	−.23	.82	<.01	.63	.08
	Left PHC	−.10	−.28–.09	−1.02	.82	.02	1.21	.14
	Left PRC	−.03	−.28–.22	−.23	.82	<.01	2.21	.23
	Right ERC	.04	−.20–.28	.31	.82	<.01	.64	.08
	Right PHC	−.09	−.26–.07	−1.12	.82	.03	2.45	.24
	Right PRC	−.04	−.28–.21	−.29	.82	<.01	1.19	.14

Note: Table 2 details the change in variance explained by CRF (estimated V̇O_2max) in separate models for young and older adults by ROI, controlling for chronological age, education, and sex. Significant results are in bold. OA: Older Adults; YA: Young Adults; ROI: region of interest, CI: confidence interval, ERC: entorhinal cortex, PHC: parahippocampal cortex, PRC: perirhinal cortex.

p < .05.

^**

p < .01.