Table 3.
main epidemiological and clinical characteristics of reported drug allergies
| Reported Cases | ||
|---|---|---|
| Age groups | Number | percentage |
| 6 months-6 years | 23 | (39.7%) |
| > 6 years -12 years | 17 | (29.3%) |
| > 12 years | 9 | (15.5 %) |
| Not Documented | 9 | (15.5%) |
| Family Atopy | ||
| Occurrence | 15 | (25.9%) |
| Not Documented | 1 | (1.7%) |
| Symptoms of the acute phase of the reaction (n=158) | ||
| Acute Urticaria | 28 | (48.3%) |
| Facial Edema | 21 | (36.2%) |
| Lips and Tongue Edema | 16 | (27.6%) |
| Wheezing Dyspnea | 11 | (19%) |
| Diarrhea | 11 | (19%) |
| Vomiting | 13 | (22.4%) |
| Rhinitis | 5 | (8.6%) |
| Conjunctivitis | 5 | (8.6%) |
| Severe Toxidermia | 14 | (24.1%) |
| Other* | 34 | (58.6%) |
| Time between drug use and reaction | ||
| Immediate | 39 | (67.2%) |
| Delayed | 15 | (25.9%) |
| Not Documented | 4 | (6.9%) |
| Treatment of the acute phase of the reaction | ||
| Antihistamines | 49 | (84.5%) |
| Corticosteroids | 44 | (75.9%) |
| Epinephrine | 11 | (19%) |
| Discontinuing of SD | 31 | (53.4%) |
| Avoidance of SD | 29 | (50%) |
| Other** | 18 | (31%) |
*
Other manifestations are isolated symptoms or combination of several symptoms (cough, cyanosis, fever, cheilitis…) which are typical and/or atypical of allergies, and which may be influenced by the nature of the suspected drug, the route of administration, and the combination of different drugs or by other physiological factors. ** For the remaining 31% of cases, additional treatments for toxidermia, contraindication of skin tests and other treatments for associated symptoms (antipyretics, antiemetics...) were prescribed and indicated.