Table 3:
Mean peak serum concentrations (Cmax) of THC and its metabolites after inhalation (INH) and i.p. administration of THC in rats (n=3 for each value, mean ± SEM).
| THC Dose and route of administration |
Cmax (ng/mL) | ||
|---|---|---|---|
| THC | 11-OH-THC | THC-COOH | |
| 2 mg/kg (i.p.) | 107.7 ± 21.9 | 84.2 ± 19.3 | 87.0 ± 21.8 |
| 0.19 mg/kg (INH) | 43.3 ± 7.2 | 14.4 ± 1.4 | 20.9 ± 4.1 |
| 0.76 mg/kg (INH) | 71.6 ± 10.9 | 35.6 ± 7.4 | 19.9 ± 2.2 |