Figure 4.

Higher satellite cell content and variability in damaged areas of repeat muscle biopsies. Representative images of Pax7 immunostaining of areas without obvious damage in nondamaged (A) and damaged (B) muscle biopsies. Pax7-positive cells are red. Pax7+ cells for nondamaged biopsies and damage-free area in damaged biopsies (labeled “damaged”) as well as areas specifically containing obvious damage (“damage containing area”) (C). Levene’s test for variance in nondamaged (D, top) and all areas of damaged (D, bottom) biopsies (P = 0.04). n = 10 for nondamaged and n = 16 for damaged groups. Scale bar 100 µm. Values are means ± SD. SC, satellite cell.