Table 1.
Baseline Mean ± SD |
P Value | ||
---|---|---|---|
Muscle Sample Characteristics | Nondamaged, n = 10 | Damaged, n = 16 | Between Group |
Muscle phenotype (CSA and distribution) | |||
Mean fiber CSA, µm2 | 4,598.01 ± 738.79 | 4,103.86 ± 845.17 | 0.13 |
Type 1 fiber CSA, µm2 | 4,549.63 ± 802.56 | 3,858.34 ± 730.22 | 0.04* |
Type 2a fiber CSA, µm2 | 4,659.04 ± 1,212.77 | 4,454.00 ± 1,093.99 | 0.67 |
Type 2a/x fiber CSA, µm2 | 3,901.71 ± 668.10 | 3,770.16 ± 1040.07 | 0.75 |
Type 1 fiber frequency, % | 50.57 ± 18.43 | 46.74 ± 11.93 | 0.57 |
Type 2a fiber frequency, % | 47.22 ± 18.31 | 49.29 ± 11.85 | 0.76 |
Type 2a/x fiber frequency, % | 2.22 ± 2.46 | 4.17 ± 7.33 | 0.35 |
Satellite cell content (SC) | |||
SC/fiber | 0.08 ± 0.04 | 0.07 ± 0.03 | 0.37 |
Total collagen content | |||
PSR/total area (%) | 5.53 ± 1.52 | 5.15 ± 1.33 | 0.53 |
Fractional synthesis rate (FSR) | |||
Protein synthesis, % per day | 2.18 ± 1.14 | 2.04 ± 1.68 | 0.80 |
RNA synthesis, % per day | 0.03 ± 0.05 | 0.04 ± 0.05 | 0.58 |
CSA, cross-sectional area; PSR, Picrosirius red. *Significantly different between groups.