Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

[Preprint]. 2024 Mar 12:2024.03.11.584540. [Version 1] doi: 10.1101/2024.03.11.584540

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This work is licensed under a Creative Commons Attribution 4.0 International License, which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.

PMC Copyright notice

LTP observed in Rem2 cKO is CaMKII dependent. After a stable baseline (30 min) was obtained myr-CN27 (1 µM) was bath applied for 50 minutes then three 100 Hz tetani were delivered with myr-CN27 still in bath after which myr-CN27 was washed out for 60 minutes. Subsequently three 100Hz tetani were delivered and the recording was continued for 60 minutes. A, B) Normalized fEPSP slope as a function of time for control (A, n = 8) and Rem2 cKO (B, n = 9). Shaded areas are the (bootstrapped) SEM. Traces above the time plots represent the raw data comprising averages of time points within each experiment taken at the time points indicated (i, ii, etc.). As before, vertical and horizontal scale lines indicate 0.5 mV and 5 ms, respectively. C, D) Summary box plot to illustrate normalized fEPSP slope for control (A, n = 8) and Rem2 cKO (B, n = 9).