Table 1.
Baseline characteristics, intraoperative characteristics and perioperative cognitive function measurements of PND and non-PND group patients.
| Feature | PND group (n = 32) | Non-PND group (n = 190) | P value |
|---|---|---|---|
| Age (yr) | 75.09 ± 4.86 | 72.35 ± 3.65 | <.001 |
| ASA classification | |||
| I | 8 (25%) | 50 (26.3%) | .95 |
| II | 15 (46.9%) | 83 (43.7%) | |
| III | 9 (28.1%) | 57 (30%) | |
| BMI (cm/kg2) | 22.41 ± 2.26 | 21.25 ± 3.21 | .52 |
| Comorbidity | |||
| Hypertension | 10 (31.3%) | 30 (15.8%) | .035 |
| Diabetes | 8 (25%) | 22 (11.6%) | .040 |
| Operation time (min) | 87.28 ± 18.09 | 93.1 ± 26.18 | .36 |
| IV fluid infusion volume (mL) | 753.12 ± 148.07 | 759.82 ± 126.28 | .78 |
| Hemorrhage volume (mL) | 86.62 ± 35.70 | 86.38 ± 45.14 | .98 |
| Preoperative MMSE score | 26.13 ± 1.77 | 26.16 ± 1.64 | .91 |
| Postoperative MMSE score | 20.16 ± 1.19 | 24.51 ± 1.52 | <.001 |
| Z-score | 3.24 ± 0.37 | 1.16 ± 0.14 | <.001 |
Data were presented as mean ± standard error.
ASA = American Society of Anesthesiologists, BMI = body mass index, IV = intravenous, MMSE = Mini-Mental State Examination, PND = perioperative neurocognitive dysfunction, postoperative MMSE score = MMSE measured 3 days after surgery, preoperative MMSE score = MMSE measured 1 day before surgery.