Table 2.
Biochemical data before and at 1 week after surgery in the remission and non-remission groups.
| Non-remission (n = 13) | P-value | Remission (n = 12) | P-value | Difference between groups | |||
|---|---|---|---|---|---|---|---|
| Before | After 1 week | Before | After 1 week | P-value | |||
| Glucose, fasting, mg/dL | 109.0 (78.0–161.5) | 117.0 (93.0–144.5) | .889 | 108.0 (81.8–124.5) | 89.0 (81.8–99.5) | .017* | .208 |
| Glucose, stimulated (30 minutes), mg/dL | 176.0 (159.5–211.0) | 206.0 (173.5–231.0) | .133 | 185.0 (161.3–223.8) | 164.5 (137.0–179.5) | .005* | .010 |
| Glucose, stimulated (60 minutes), mg/dL | 251.0 (210.0–279.5) | 254.0 (210.5–281.0) | .861 | 232.0 (211.0–289.3) | 220.5 (152.0–236.3) | .015* | .070 |
| Glucose, stimulated (90 minutes), mg/dL | 267.0 (251.5–285.0) | 252.0 (216.5–297.5) | .345 | 255.0 (237.5–286.5) | 211.0 (167.3–242.8) | .008* | .285 |
| Glucose, stimulated (120 minutes), mg/dL | 275.0 (241.0–321.5) | 223.0 (189.5–276.5) | .003* | 241.0 (178.0–296.3) | 178.0 (146.8–237.3) | .015* | .888 |
| Insulin, fasting, μIU/mL | 9.3 (5.9–14.2) | 5.8 (4.8–7.4) | .019* | 9.1 (7.3–15.3) | 4.8 (2.5–6.0) | .002* | .969 |
| Insulin, stimulated (30 minutes), μIU/mL | 14.7 (11.2–37.5) | 9.4 (7.7–17.6) | .071 | 21.4 (13.7–32.9) | 12.1 (7.9–16.8) | .016* | .972 |
| Insulin, stimulated (60 minutes), μIU/mL | 21.4 (12.7–48.8) | 18.0 (10.5–24.6) | .279 | 30.2 (17.6–48.3) | 13.0 (7.5–35.0) | .594 | .748 |
| Insulin, stimulated (90 minutes), μIU/mL | 23.9 (17.5–52.8) | 28.7 (12.3–35.0) | .311 | 40.1 (21.6–66.7) | 19.7 (16.6–30.8) | .346 | .943 |
| Insulin, stimulated (120 minutes), μIU/mL | 21.9 (15.4–54.9) | 17.3 (9.7–36.1) | .173 | 29.3 (22.4–43.6) | 15.1 (11.6–36.8) | .158 | .945 |
| HOMA-IR | 2.2 (1.2–4.3) | 1.8 (1.0–2.5) | .184 | 2.7 (1.7–3.7) | 1.1 (0.5–1.3) | .002* | .793 |
| Matsuda index | 4.7 (2.8–8.8) | 6.8 (4.6–10.7) | .530 | 4.0 (2.9–5.7) | 7.9 (7.1–14.9) | .008* | .055 |
| HOMA-β | 70.3 (47.7–212.6) | 36.2 (22.5–66.6) | .023* | 65.0 (47.4–144.7) | 62.2 (36.5–111.6) | .308 | .143 |
| Insulinogenic index | 0.08 (0.03–0.11) | 0.07 (0.03–0.13) | .529 | 0.18 (0.07–0.28) | 0.13 (0.09–0.18) | .533 | .425 |
| Body weight, kg (n = 12) | 71.0 (64.8–82.1) | 68.1 (60.6–80.2) | .004* | 71.6 (64.3–78.5) | 68.8 (60.1–75.5) | .008* | .657 |
| BMI (n = 12) | 26.2 (24.0–28.0) | 24.5 (22.4–27.0) | .004* | 26.0 (24.4–28.4) | 25.0 (22.8–27.6) | .006* | .675 |
Values are presented as medians (interquartile range).
Remission: HbA1c level after 1 year was <6.0% without medication.
BMI = body mass index, HOMA-IR = homeostasis model assessment: estimated insulin resistance, HOMA-β = homeostasis model assessment of β-cell function.
*
Statistically significant preoperative data vs 1 week after surgery data, as shown by Mann–Whitney U test.