Table 3.
The effect of baseline factors on the probability of diabetes remission at the 1-year visit.
| Variables | Univariable Model | P-value | Multivariable Model | P-value |
|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | |||
| Duration of diabetes (years) | 0.75 (0.58–0.96) | .024 | Adjusted* | |
| Age (years) | 1.02 (0.90–1.17) | .717 | 1.00 (0.86–1.16) | .957 |
| Female sex | 0.30 (0.03–3.41) | .334 | 0.37 (0.03–5.20) | .458 |
| Medication history before surgery | 0.55 (0.07–4.01) | .551 | 1.29 (0.11–15.28) | .841 |
| Metabolic parameters, before surgery | ||||
| HbA1c, % | 0.70 (0.37–1.34) | .287 | 0.81 (0.40–1.64) | .553 |
| BMI, kg/m2 | 1.10 (0.83–1.46) | .501 | 1.31 (0.91–1.90) | .147 |
| Glucose, fasting, mg/dL | 1.00 (0.98–1.02) | .797 | 1.00 (0.98–1.02) | .994 |
| Glucose, stimulated (30 minutes), mg/dL | 0.99 (0.98–1.00) | .170 | 1.01 (0.99–1.03) | .519 |
| Glucose, stimulated (60 minutes), mg/dL | 0.99 (0.98–1.00) | .157 | 1.01 (0.99–1.03) | .394 |
| Glucose, stimulated (90 minutes), mg/dL | 0.99 (0.98–1.00) | .047 | 1.00 (0.98–1.02) | .998 |
| Glucose, stimulated (120 minutes), mg/dL | 0.99 (0.98–1.00) | .033 | 1.00 (0.98–1.01) | .500 |
| HOMA-IR | 0.94 (0.78–1.13) | .496 | 0.94 (0.78–1.13) | .511 |
| HOMA-β | 1.00 (0.99–1.00) | .474 | 1.00 (0.99–1.00) | .609 |
| Insulinogenic index ≥ 0.095 (M) | 6.00 (1.02–35.37) | .048 | 3.96 (0.51–30.52) | .187 |
| Parameters of OGTT after 1 week | ||||
| BMI, kg/m2 | 1.07 (0.84–1.38) | .574 | 1.25 (0.90–1.72) | .183 |
| Glucose, fasting, mg/dL | 0.96 (0.92–1.00) | .031 | 0.96 (0.92–1.00) | .075 |
| Glucose, stimulated (30 minutes), mg/dL | 0.96 (0.93–1.00) | .026 | 0.96 (0.92–1.00) | .043 |
| Glucose, stimulated (60 minutes), mg/dL | 0.98 (0.96–1.00) | .041 | 0.98 (0.95–1.00) | .060 |
| Glucose, stimulated (90 minutes), mg/dL | 0.98 (0.96–1.00) | .039 | 0.98 (0.95–1.00) | .057 |
| Glucose, stimulated (120 minutes), mg/dL | 0.98 (0.96–1.00) | .054 | 0.98 (0.96–1.00) | .077 |
| HOMA-IR | 0.18 (0.02–0.72) | .021 | 0.09 (0.01–0.90) | .041 |
| HOMA-β | 1.01 (0.99–1.03) | .229 | 1.01 (0.99–1.02) | .369 |
| Insulinogenic index ≥ 0.1 (M) | 4.00 (0.73–21.84) | .109 | 2.36 (0.34–16.18) | .383 |
The association between each baseline characteristics and diabetes remission at the 1-year visit is presented as an OR and its CI estimated using logistic regression analysis.
Significant values (P < .05) are in boldface type.BMI = body mass index, CI = confidence interval, HbA1c = hemoglobin A1c, HOMA-IR = homeostasis model assessment: estimated insulin resistance, HOMA-β = homeostasis model assessment of β-cell function, (M) = median value, OGTT = oral glucose tolerance test, OR = odds ratio.
*
Each variable was adjusted with duration of diabetes in multivariable model.