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. 2022 Sep 9;101(36):e30352. doi: 10.1097/MD.0000000000030352

Table 3.

Crude and adjusted odds ratios (95% CI) of increased 10-year risk scores (≥5%) for atherosclerotic cardiovascular disease in postmenopausal women according to oral glucose tolerance status.

NGT IGT IPH
Scenario 1
 No. of subjects (10-yr ASCVD risk score ≥5% vs <5%) 15/121 43/171 25/53
 Model 1 1.0 2.03 (1.08–3.82)* 3.81 (1.86–7.79)***
 Model 2 1.0 1.92 (1.01–3.62)* 3.35 (1.62–6.92)**
 Model 3 1.0 1.96 (0.98–3.89) 3.28 (1.47–7.36)**
Scenario 2
 No. of subjects (10-yr ASCVD risk score ≥5% vs <5%) 15/121 43/171 56/22
 Model 1 1.0 2.03 (1.08–3.82)* 20.53 (9.91–42.55)***
 Model 2 1.0 1.89 (0.99–3.58) 19.03 (9.08–39.90)***
 Model 3 1.0 1.87 (0.93–3.78) 26.74 (11.47–62.34)***

Data are expressed odds ratios (95% CI).

Model 1, no adjustment; Model 2, further adjusted for BMI; Model 3, further adjusted for physical inactivity score, Log ALT, serum Cr, hypertension treatment (yes vs no), and Hormone replacement (yes vs no).

ALT = alanine aminotransferase, ASCVD = atherosclerotic cardiovascular disease, BMI = body mass index, CI = confidence intervals, Cr = creatinine, IGT = impaired glucose tolerance, IPH = isolated postchallenge hyperglycemia, Log ALT = logarithmic transformation of ALT (in U/L), NGT = normal glucose tolerance.

Scenario 1: subjects with IPH were not designated as patients of diabetes mellitus while performing ASCVD risk estimation.

Scenario 2: subjects with IPH were designated as patients of diabetes mellitus while performing ASCVD risk estimation.

*

P < .05 versus NGT by logistic regression analysis.

**

P < .01 versus NGT by logistic regression analysis.

***

P < .0001 versus NGT by logistic regression analysis.