Table 2.
Logistic regression analysis of the risk factors for EOS in preterm infants.
| Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| OR (95% CI) | P value* | OR (95% CI) | P value† | |
| Sex | ||||
| Male | Ref | Ref | ||
| Female | 1.53 (0.87–2.69) | .144 | 0.96 (0.34–2.68) | .937 |
| Birth weight (g) | 1 (1–1) | <.001 | 1 (1–1) | .711 |
| Gestational age, (%) | ||||
| <28 wk | Ref | Ref | ||
| 28–31+6 wk | 0.3 (0.09–1.01) | .053 | 0.18 (0.03–1.11) | .065 |
| 32–33+6 wk | 0.13 (0.04–0.49) | .002 | 0.04 (0–0.43) | .007 |
| 34–36+6 wk | 0.03 (0.01–0.09) | <.001 | 0.01 (0–0.14) | .001 |
| WBC (109/L) | 1.27 (1.16–1.4) | <.001 | 0.98 (0.78–1.22) | .837 |
| NLR | 1.77 (1.5–2.09) | <.001 | 1.67 (1.18–2.36) | .004 |
| PLR | 1.03 (1.02–1.04) | <.001 | 1.03 (1.01–1.04) | .001 |
| MPV (fL) | 0.88 (0.74–1.05) | .155 | 1.75 (1.15–2.66) | .009 |
| Mode of delivery | ||||
| Cesarean section | Ref | Ref | ||
| Normal delivery | 0.96 (0.5–1.85) | .914 | 1.47 (0.44–4.88) | .529 |
| Ppom (h) | 1 (1–1.01) | .168 | 1 (0.99–1.01) | .535 |
| Fever, n (%) | ||||
| T < 38°C | Ref | Ref | ||
| T ≥ 38°C | 1.73 (0.53–5.65) | .364 | 5.11 (0.82–31.91) | .081 |
| Vaginitis, n (%) | ||||
| No | Ref | Ref | ||
| Yes | 2.43 (0.59–10.01) | .219 | 5.73 (0.79–41.67) | .085 |
| Amniotic fluid degree III°, n (%) | ||||
| No | Ref | Ref | ||
| Yes | 1.6 (0.44–5.86) | .478 | 1.13 (0.07–17.6) | .931 |
CI = confidence interval, MPV = mean platelet volume, NLR = neutrophil to lymphocyte ratio, OR = odds ratio, PLR = platelet to lymphocyte ratio, Ppom = premature rupture of membranes, Ref = reference, T = temperature, WBC = white blood cell count.
*
P for the result of univariate analysis.
†
P for the result of multivariate analysis.