Table 3.

Global volumes in PD patients and HCs.

Structure	PD patients (n = 34, mean ± SD)			HCs (n = 32, mean ± SD)			pc
	Baseline	Follow-up	pa	Baseline	Follow-up	pb
Left caudate	3447.92 ± 464.09	3399.10 ± 504.78	0.128	3391.04 ± 355.91	3343.50 ± 422.60	0.469	0.850
Right caudate	3508.68 ± 485.36	3471.22 ± 504.28	0.125	3444.38 ± 440.18	3421.56 ± 411.87	0.469	0.850
Left pallidum	1900.46 ± 225.15	1873.34 ± 224.52	0.125	1887.19 ± 275.30	1888.59 ± 285.47	0.939	0.826
Right pallidum	1863.70 ± 198.70	1859.07 ± 200.71	0.827	1806.62 ± 195.25	1807.98 ± 213.13	0.939	0.850
Left putamen	4862.25 ± 610.10	4795.41 ± 667.05	0.125	4825.53 ± 479.80	4842.78 ± 550.47	0.939	0.826
Right putamen	4774.19 ± 584.03	4728.68 ± 641.03	0.382	4689.69 ± 505.38	4728.79 ± 512.30	0.469	0.826
Left thalamus	7978.53 ± 733.48	7974.82 ± 702.55	0.951	7806.80 ± 632.79	7795.97 ± 580.59	0.939	0.850
Right thalamus	7817.62 ± 684.83	7788.43 ± 683.82	0.827	7684.96 ± 601.62	7643.58 ± 619.47	0.800	0.826

^a,bPaired t-test between baseline and follow-up.

^cGroup comparison between PD patients ang HCs at baseline using general linear model.

*p < 0.05. **p < 0.01. All P-values were FDR-adjusted.