Fig. 1. Diagnosed and unexpected disease.

a Schematic of all clinically diagnosed sites of disease throughout each patient’s history up until death. b Clinically diagnosed disease sites shaded in gray. Purple shading indicates diseases identified at postmortem that were not previously diagnosed or suspected while the patient was alive. Green shading indicates the presence of micrometastases that were identified in “disease-free” tissues via immunofluorescence (IF) Figures created with BioRender.com.