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. 2024 Mar 15;8:e52809. doi: 10.2196/52809

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©Kyra Henderson, Jennifer Reihm, Kanishka Koshal, Jaeleene Wijangco, Narender Sara, Nicolette Miller, Marianne Doyle, Alicia Mallory, Judith Sheridan, Chu-Yueh Guo, Lauren Oommen, Katherine P Rankin, Stephan Sanders, Anthony Feinstein, Christina Mangurian, Riley Bove. Originally published in JMIR Formative Research (https://formative.jmir.org), 15.03.2024.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Formative Research, is properly cited. The complete bibliographic information, a link to the original publication on https://formative.jmir.org, as well as this copyright and license information must be included.

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The sequence of iterative feedback and human-centered design (HCD) development leading to tool optimization over 9 months, including activities, participants, and outcomes. COM-B: capability, opportunity, and motivation model for behavioral change; Health ITUES: Health IT Usability Evaluation Scale; MS: multiple sclerosis; MS CATCH: Care Technology to Ascertain, Treat, and Engage the Community to Heal Depression in people living with multiple sclerosis UCSF: University of California, San Francisco.