Database	Search strategy
PubMed	#1 “Dementia, Vascular” [Mesh]
	#2 Vascular dementia OR vascular dement* OR vascular cognitive impairment*
	#3 VaD OR VCI
	#4 #1 OR #2 OR #3
	#5 “3-n-butylphthalide” [Supplementary Concept]
	#6 DL-3-n-butylphthalide OR l-NBP cpd OR N-butylphthalide OR butylphthalide OR (S)-(-)-3-butylphthalide OR NBP
	#7 #5 OR #6
	#8 “Donepezil”[Mesh]
	#9 Donepezilium Oxalate Trihydrate OR E 2020 OR E2020 OR Donepezil Hydrochloride OR 1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl) methylpiperidine hydrochloride OR Aricept
	#10 #8 OR #9
	#11 #7 AND #10
	#12 (randomized controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab] OR clinical trials as topic[mesh:noexp] OR randomly[tiab] OR trial[ti] NOT (animals[mh] NOT humans [mh]))
	#13 #4 AND #11 AND #12