Table 2.
Decomposition of ischemic stroke deaths attributed to high low-density lipoprotein cholesterol from 1990 to 2019 according to population growth, aging, and epidemiological changes at the global level, 21 GBD region level, and quintile SDI region level.
| Location | Overall difference | Aging (Percent) | Population (Percent) | Epidemiological changes (Percent) |
|---|---|---|---|---|
| Global | 198088.04 | 167395.82 (84.51%) | 299031.12 (150.96%) | −268338.90 (−135.46%) |
| Socio-demographic Index Regions | ||||
| High SDI | −25751.33 | 54411.95 (−211.30%) | 38818.76 (−150.74%) | −118982.04 (462.04%) |
| High-middle SDI | 48026.27 | 79017.95 (164.53%) | 96178.87 (200.26%) | −127170.55 (−264.79%) |
| Middle SDI | 113324.09 | 47836.90 (42.21%) | 80670.81 (71.19%) | −15183.61 (−13.40%) |
| Low-middle SDI | 48857.91 | 15353.16 (31.42%) | 36356.94 (74.41%) | −2852.19 (−5.84%) |
| Low SDI | 13507.43 | 800.49 (5.93%) | 12515.95 (92.66%) | 190.99 (1.41%) |
| GBD Regions | ||||
| Andean Latin America | 881.75 | 465.78 (52.82 %) | 1100.88 (124.85%) | −684.90 (−77.68%) |
| Australasia | 204.71 | 1358.11 (663.43%) | 1157.68 (565.52%) | −2311.08 (−1128.94%) |
| Caribbean | 1658.73 | 833.42 (50.24 %) | 1371.93 (82.71 %) | −546.62 (−32.95%) |
| Central Asia | 2356.23 | −1114.74 (−47.31%) | 3566.78 (151.38%) | −95.81 (−4.07%) |
| Central Europe | −58.65 | 15059.28 (−25674.40%) | 3734.01 (−6366.06%) | −18851.94 (32140.46%) |
| Central Latin America | 3945.35 | 2959.86 (75.02 %) | 4954.05 (125.57%) | −3968.56 (−100.59 %) |
| Central Sub-Saharan Africa | 1382.88 | 63.73 (4.61%) | 1449.16 (104.79%) | −130.01 (−9.40%) |
| East Asia | 117420.24 | 61234.56 (52.15 %) | 65185.07 (55.51%) | −8999.39 (−7.66%) |
| Eastern Europe | −6006.98 | 27290.38 (−454.31%) | 4559.34 (−75.90%) | −37856.70 (630.21 %) |
| Eastern Sub-Saharan Africa | 4003.78 | −58.80 (−1.47 %) | 3488.24 (87.12%) | 574.33 (14.34%) |
| High-income Asia Pacific | 3194.09 | 26685.46 (835.46 %) | 7204.59 (225.56 %) | −30695.96 (−961.02%) |
| High-income North America | −8402.91 | 8714.28 (−103.71%) | 9362.97 (−111.43%) | −26480.16 (315.13%) |
| North Africa and Middle East | 27284.79 | 3067.68 (11.24%) | 25374.74 (93.00 %) | −1157.64 (−4.24%) |
| Oceania | 190.67 | 14.19 (7.44 %) | 175.53 (92.06 %) | 0.95 (0.50 %) |
| South Asia | 33545.98 | 13771.55 (41.05 %) | 27278.34 (81.32 %) | −7503.91 (−22.37 %) |
| Southeast Asia | 32276.58 | 9380.77 (29.06 %) | 21508.29 (66.64 %) | 1387.53 (4.30 %) |
| Southern Latin America | 535.43 | 1348.46 (251.85 %) | 1954.99 (365.13 %) | −2768.02 (−516.97%) |
| Southern Sub-Saharan Africa | 1962.42 | 90.18 (4.60 %) | 1530.82 (78.01%) | 341.42 (17.40 %) |
| Tropical Latin America | 4489.88 | 7311.83 (162.85 %) | 10471.15 (233.22%) | −13293.10 (−296.07%) |
| Western Europe | −26811.72 | 35214.69 (−131.34 %) | 16408.33 (−61.20%) | −78434.74 (292.54%) |
| Western Sub-Saharan Africa | 4034.80 | −599.72 (−14.86 %) | 5329.16 (132.08%) | −694.64 (−17.22%) |
Note: “−” of percentage indicates the direction of deaths change related to each factor is opposite to the overall difference. GBD: global burden of disease. SDI: socio-demographic index.