Table 1.

Questions addressing Y-90 TARE recommendations in lmCRC

Process	Questions
General issues	1. Which members should be part of the multidisciplinary tumor committee (MTC) for the selection of patients who are candidates for Y-90 TARE?
	2. What are the indications for treatment with Y-90 TARE?
	3. What are the contraindications for Y-90 TARE?
Previous process	4. Are there biomarkers that can predict candidate patients for Y-90 TARE treatment?
	5. What are the preintervention tests with Y-90 TARE?
	6. What is the evidence for Y-90 TARE treatment in lmCRC?
Procedure	7. What is the standard procedure for Y-90 TARE?
Post-intervention follow-up	8. What is the potential toxicity of Y-90 TARE, and how is it handled?
	9. What parameters are used for the evaluation of Y-90 TARE response?
	10. How does Y-90 TARE impact the quality of life of the patient with lmCRC?