Fig. 7.

Treg depletion augments IL7 mediated tumor growth delay. A Experimental schematic with timing of RT, aCD25, and IL7 injections. RT was administered in two 4 Gy fractions. IL7 was administered three times a week via i.p. injection for 2 weeks, and aCD25 was given via i.p. injection once per week. B Tumor growth curves for each treatment group (n = 10 for each group). Black arrow indicates RT administration; yellow arrow indicates IL7 injection; red arrow indicates aCD25 injection. C Individual tumor growth curves for all cohorts. Statistics were calculated using one-way ANOVA (B). The mean ± SEM is shown (B). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001