Table 3.
Diagnostic efficacy of MAGEA3 and MAGEA4 mRNA in serum and serum exosome and diagnostic efficacy of MAGEA3 protein in serum.
| Variables | AUC (95% CI) | Cut off | Sensitivity (%) | Specificity (%) | |
|---|---|---|---|---|---|
| mRNA expression | Serum MAGEA3 | 0.721 (0.631–0.812) | 0.358 | 58.70 | 77.10 |
| Serum MAGEA4 | 0.670 (0.577–0.764) | 0.261 | 99.00 | 27.10 | |
| Exosome MAGEA3 | 0.832 (0.741–0.923) | 0.538 | 95.20 | 58.60 | |
| Exosome MAGEA4 | 0.827 (0.741–0.913) | 0.475 | 56.60 | 90.00 | |
| Protein expression | Serum MAGEA3 | 0.781 (0.686–0.876) | 0.533 | 82.10 | 72.10 |