Comparison 6. High‐dose intravenous omalizumab + steroid versus placebo + steroid (stable steroid).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Rescue medication usage	1		Std. Mean Difference (IV, Fixed, 95% CI)	Totals not selected
1.1 Mild asthma	0		Std. Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
1.2 Moderate to severe asthma	1		Std. Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
1.3 Severe asthma	0		Std. Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
2 Morning PEF	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
2.1 Mild asthma	0		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
2.2 Moderate to severe asthma	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
2.3 Severe asthma	0		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
2.4 Moderate to severe	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
3 Symptom scores	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
3.1 Mild asthma	0		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
3.2 Moderate to severe asthma	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
3.3 Severe asthma	0		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
4 Quality of life	1		Std. Mean Difference (IV, Fixed, 95% CI)	Totals not selected
4.1 Mild asthma	0		Std. Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
4.2 Moderate to severe asthma	1		Std. Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
4.3 Severe asthma	0		Std. Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
5 Number of participants with > 50% reduction in symptom score	1		Odds Ratio (M‐H, Fixed, 95% CI)	Totals not selected
5.1 Moderate to severe asthma	1		Odds Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
5.2 Severe asthma	0		Odds Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]