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. 2024 Mar 30;23:28. doi: 10.1186/s12941-024-00688-1

Table 3.

Positive and negative predictive value, sensitivity and specificity of LAMP-CRISPR/Cas for the detection of N. meningitidis in clinical samples

LAMP-CRISPR/Cas Real-time PCR PPV NPV Sensitivity Specificity
Positive Negative Total Number/ Total number (%)
Positive 50 1 51

50/51

(98.04)

50/55

(90.91)

Negative 5 83 88

83/88

(94.31)

83/84

(98.81)

Total 55 84 139

PPV: positive predictive value; negative predictive value (NPV)