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. 2024 Mar 30;23:111. doi: 10.1186/s12933-024-02209-y

Table 3.

HRs (95% CIs) for all-cause mortality according to the TyG index

Characteristic model 1 model 2 model 3
HR1 95% CI1 P-value HR1 95% CI1 P-value HR1 95% CI1 P-value
All participants
Continous 1.29 1.21, 1.37 < 0.001 1.19 1.08, 1.30 < 0.001 1.21 1.09, 1.33 < 0.001
TyG index
 Q1
 Q2 1.35 1.14, 1.60 < 0.001 0.98 0.84, 1.14 0.8 1.01 0.86, 1.18 > 0.9
 Q3 1.48 1.26, 1.73 < 0.001 1.03 0.90, 1.18 0.7 1.05 0.91, 1.21 0.5
 Q4 1.64 1.42, 1.89 < 0.001 1.18 1.02, 1.36 0.021 1.19 1.03, 1.37 0.021
P for trend < 0.001 < 0.001 < 0.001
Pain
Continous 1.18 1.02, 1.36 0.029 1.13 0.96, 1.34 0.13 1.14 0.94, 1.37 0.2
TyG index
 Q1
 Q2 1.14 0.82, 1.58 0.4 0.90 0.64, 1.26 0.5 0.90 0.65, 1.27 0.6
 Q3 1.22 0.92, 1.61 0.2 0.88 0.67, 1.16 0.4 0.88 0.67, 1.15 0.3
 Q4 1.45 1.09, 1.94 0.010 1.12 0.85, 1.48 0.4 1.13 0.84, 1.50 0.4
P for trend 0.065 0.065 0.065
No pain
Continous 1.33 1.21, 1.46 < 0.001 1.20 1.05, 1.37 0.007 1.25 1.09, 1.43 0.002
TyG index
 Q1
 Q2 1.45 1.14, 1.83 0.002 1.02 0.83, 1.25 0.9 1.06 0.86, 1.32 0.6
 Q3 1.60 1.27, 2.01 < 0.001 1.10 0.90, 1.35 0.4 1.15 0.93, 1.42 0.2
 Q4 1.68 1.33, 2.13 < 0.001 1.18 0.94, 1.49 0.2 1.22 0.96, 1.54 0.10
P for trend < 0.001 < 0.001 < 0.001

HR = Hazard Ratio, CI = Confidence Interval

Model 1: Unadjusted

Model 2: Adjusted for age, sex, and BMI

Model 3: Adjusted for age, sex, BMI, race, education, smoking status, total cholesterol, hypertension, heart failure, coronary heart disease, angina, heart attack, stroke, antihyperlipidemic agents, and antidiabetic agents