Fig. 10.

In panel A, fits (solid red lines) and simulation (dashed blue lines) of the NODE with Eqs. (10, 11) trained on data (red circles) generated with the one-compartment PO ODE model with 8 transit compartments for different dose levels is shown. In panels B and C, fits and simulation of the NODE with Eqs. (12, 13) trained on data generated with the original TMDD model with extravascular administration for different doses is shown in linear and in semi log scale, respectively