Fig. 5.

In panel A, simulated data (blue triangles) for dose $d$ = 20 with the original ODE model and the NODE Eq. (6) trained on a dose $d$ = 1 (dashed blue line) is shown. In panel B, the corresponding derivative versus state plot indicates the inability of NNs to extrapolate which inherits to the NODE. In panel C and D, simulated data for different unseen doses ($d$ = 5, 10, 20 and 35) with the original ODE model and the NODE Eq. (6) trained on two dose levels $d$ = 1 and $d$ = 50 is shown and the corresponding plots indicate the interpolation capability of NNs