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. 2023 Oct 14;51(2):123–140. doi: 10.1007/s10928-023-09886-4

Fig. 8.

Fig. 8

Data applied for training (red circles) and simulation (blue triangles) generated with a one-compartment IV infusion ODE model, see panel A. Furthermore, fits of the trained NODE Eq. (9) for the two training doses (solid red line) and simulations (dashed blue lines) are presented. In panel B, the corresponding derivative versus state plot indicates that the NODE learned the mechanism well