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Summary of the disadvantages of THRIVE described in the literature
| Requires specialised oxygen delivery equipment |
| Cost of machine and associated disposable equipment |
| Success is dependent of anaesthetist experience |
| Success is dependent on patient factors including age, BMI, OSA, cardiorespiratory status, smoking history, hypermetabolic states, and presence of upper airway pathology |
| No aspiration protection |
| End tidal CO2 is not monitored |
